Looking for great pizza in Clarksdale? Domino’s is your go-to destination for delicious pizza and a wide range of mouthwatering menu options. Whether you’re craving classic pepperoni pizza, cheesy pasta, stuffed cheesy bread, flavorful salads, or chicken wings, our Clarksdale pizza location has got you covered.
Enjoy the convenience of delivery, carryout, or curbside pickup with our exclusive Domino’s Carside Delivery service. Wherever you are, we have an option for pizza near you. Explore our menu, discover local coupons, and track the status of your lunch, dinner, or late-night order at 640 Desoto Avenue.
Delivery/carryout chain offering a wide range of pizzas & a variety of other dishes & sides. Based on 176 reviews, the restaurant has received a rating of 4.0 stars. Price $
✔️ Curbside pickup ✔️ No-contact delivery ✔️ No dine-in

Address:
640 Desoto Ave, Clarksdale, MS 38614
Phone: (662) 627-5030
Website:
Hours
| Monday
(Labor Day)
|
10:30 AM–12 AM
Hours might differ
|
| Tuesday |
10:30 AM–12 AM |
| Wednesday |
10:30 AM–12 AM |
| Thursday |
10:30 AM–12 AM |
| Friday |
10:30 AM–1 AM |
| Saturday |
10:30 AM–1 AM |
| Sunday |
10:30 AM–12 AM |
Photo Gallery
Reviews
Pamela Ross
Working the Frontline and preparing to go to work, picked up pizza before time to go in. After a couple of slices, I recognized order was missing one ingredient, thought perhaps it was just scarcely applied – but I confirmed it was not there. Called shop to inform of missing ingredient. They told me to bring the pizza back so they could see it. There was no other way they offered to make it right even when I explained I needed to prepare for work. I returned the pizza as they instructed. They acknowledged it was made wrong and made me another pizza with the ordered ingredients. Except this time the pizza dough was not fully cooked. Could tell by the weight of the box that the one added ingredient was not going to be THAT heavy. Got home to find inadequately cooked pizza dough beneath the mound of ingredients. The waste of my money is not nearly as valuable as their waste of my time today. I’m taking a break from this place.
… more
Madison Howard
The price is worth it, and the pizza is SO DELICIOUS I could eat it endlessly.
… more
Rockrguy 90
Good thing this is the last time we are ordering from this place, just sub par all the time. The lack of competition makes them lazy and have no care in what they are making. Whoever franchises this location has no care at all about the store, they basically rob you with putting barely any toppings on the pizzas and they are wrong 98% of the time just a shame
… more
Nicki Giles-Robinson
I ordered a carry out pizza, went in to pick it up and I didn’t see the young lady that took my money or no one washing their hands after touching different things with their bare hands, a guy came from the back with his hair all over his head and strings of hanging hair looking like it’s about to fall off while walking around the pizza work station with no hair net on, one young lady went to the back and got a bag of pepperoni just opened the bag and preceded to put them out without washing her hand and continued to make a pizza, they need to get sanitizing and contamination training as well as preventing the spread of germs, talking over the pizza while preparing them, I say this because Covid-19 and other variants are still present, as for me I have a compromised immune system and underlying aliaments so let’s beware of what we do
… more
Harley Cole
Excellent pizza, great service. I like their tracking t.v. they have inside their shop. I was actually there and ordered 3 pizzas last night, and they were extremely nice and helpful.
… more
St. George’s Church
I’ve never had a problem when ordering from this Domino’s, either in person, over the phone or online. The delivery person is always polite. The order is always correct, & delicious. I love Domino’s. I would recommend this store.
… more
Sharon Thomas
Hot and good an also bought cheese stuff bread sticks
… more
Ladi Review
Delivery is quick. Pizza is okay, but could be much better. If they would just add a little more sauce and cheese, their pizza would be great. If you can see the crust beneath the toppings then your pizza is dry and lacking sustenance. Do better Domino’s.
… more
Vallenry Thomas
I ordered online. My order was ready when I arrived. The pizza was good. The employees were nice and acted in a professional manner.
… more
R
Probably been a year since I’ve had domino’s And it’s still my favorite And the service was great very Accurate on the time. They told me when it was going to be ready I walked in the door and they took it out of the oven and handed it to me Great service
… more
… View more